As labs are updated and become more modern, better methods of data management and record-keeping may be necessary to maintain or improve efficiency.  Luckily, there is a means to achieve this: Laboratory Information Management Systems, or LIMS.

With the increase in disease and the growth in the medical diagnosis sector, the number of samples collected is increasing day by day. With the help of Machine interfacing, labs can handle a large volume of samples easily, increasing the efficiency of sample processing and the quality of lab reports.

Types of Machine Interfacing in Laboratory Information Management System(LIMS):


Uni-Directional Instruments:

Overview: Uni-directional instruments operate on a one-way communication system, facilitating the seamless transfer of information from the samples to the Laboratory Information Management System (LIMS). In this setup, results are stored within the LIMS database upon the completion of the test process. Unlike bi-directional instruments, which support two-way communication, uni-directional instruments focus on unidimensional data flow.

Workflow Process: The workflow involves manual sample placement by the technician, who assumes the responsibility of strategically positioning samples for analysis. Additionally, the technician plays a crucial role in determining the specific type of sampling method to be employed. This hands-on approach ensures that the instrument receives accurate and relevant data for subsequent processing.

Result Storage: Upon completion of the test, the results are systematically stored in the LIMS database. This unidirectional flow of information simplifies data management, with the LIMS acting as a centralized repository for comprehensive result storage. This streamlined process contributes to the efficiency of data retrieval and analysis within the laboratory setting.

Technician Involvement: The technician's involvement is pivotal in the uni-directional instrument setup, as they guide the initial placement of samples and make informed decisions about the sampling technique. This level of manual intervention ensures precision and control over the testing process, aligning with the laboratory's specific requirements and protocols.

Uni-directional instruments, by emphasizing one-way communication and manual input from skilled technicians, contribute to a structured and controlled laboratory environment where data accuracy and integrity are paramount.

Bi-directional Instruments:

Advanced Functionality: Bi-directional instruments represent a higher level of sophistication and advancement in laboratory technology. These instruments possess the capability to not only generate output data reports and results but also feature an Application Programming Interface (API). This advanced functionality enables the seamless exchange of data, information, commands, functions, and worklists with the system.

Output Data Reports: One key feature of bi-directional instruments is their ability to generate comprehensive output data reports. These reports provide a detailed analysis of test results and relevant information, offering a comprehensive view of the findings. The generated reports serve as valuable documentation for further analysis and decision-making processes.

Results Generation: Bi-directional instruments excel at producing accurate and timely results. The dual communication capabilities allow for efficient data transfer, ensuring that results are not only generated promptly but also transmitted seamlessly to the designated system or database.

Application Programming Interface (API): A defining feature of bi-directional instruments is the inclusion of an Application Programming Interface (API). This interface facilitates the exchange of data, information, and commands between the instrument and the broader laboratory system. The API functionality enhances interoperability, enabling the instrument to import and export data with ease.

Enhanced Connectivity: Bi-directional instruments contribute to enhanced connectivity within the laboratory ecosystem. The ability to import data, information, commands, functions, and worklists through the API fosters a dynamic and integrated environment. This connectivity streamlines laboratory processes, promoting efficiency and accuracy in data handling.

Our LIMS System sends commands to the sampling unit on the type of sampling to be conducted with the given sample. After the testing is done by the LIMS command, the results are auto-fetched on the LIMS Server. The bi-directional instruments are interfaced with the LIMS system programmatically.

The Need to Interface Instruments with LIMS Software:


There are several reasons why it is beneficiary to interface lab instruments with LIMS Software. Let us look into a few reasons here:

Increase in Productivity by Effective Machine Utilization:

Interfacing your instruments with your LIMS Software is a one-time investment of cost and work with a repetitive increase in lab productivity and effectiveness. Interfacing LIMS Software with your lab instruments removes many complexities like manual entering of data every time or referring data from other instruments to the LIMS. This altogether saves a lot of time and effort when done by a LIMS rather than manually, also avoiding any human errors during data entry.

Utilizing machines effectively can increase productivity drastically.  When the task is done manually, very few samples are completely analyzed in the given period, but with MI they can perform many sample processing and that will increase machine utilization and increase revenue.

Increase in Data Quality by Reducing Manual Errors:

The second best reason for interfacing your lab instruments with your LIMS Software is the increase in data quality and integrity. As a human, we are eligible to commit human errors that might not be over-influential over the system as a whole but might still be considered an error. By removing human interference, these errors are avoided thereby guaranteeing better data transfer in the system.

Similarly, transcribing data into the system by people can also lead to common errors affecting the quality of data. Data integrity is considered a very important issue in laboratories. By interfacing your instruments to your LIMS System, you will eliminate this issue.

Saves Time in output generation thereby satisfying the patients:

Machine Interfacing helps to analyze the given samples at a faster rate and generates quality results within a shorter duration of time. After the result processing is done, the report will be generated manually.

With the use of MI, ultimate patient satisfaction can be achieved by generating the results in a quick manner with good quality.

Machine interfacing in laboratories is more of a comfort rather than a negative factor. What might be a one-time investment in your labs can save a lot of time and work when interfaced properly with your systems.



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An Introduction to LIMS Software:

Laboratory Information Management System (LIMS) is software that is used in labs for data management and to process a large number of lab samples to manage laboratory workflow. With LIMS, the lab can automate workflows, integrate instruments, and manage samples and associated information. Additionally, labs can produce valid results quickly and can track data across experiments to improve efficiency.

LIMS that are commonly used in clinical labs fall under the following categories:


The benefits of using LIMS Software in your lab are:

  • Workflow automation
  • Integrate instruments or other in-lab systems
  • Centralize access and storage of data
  • Track data from sequencing runs
  • Initiate downstream data analysis

The Efficiency of LIMS System:

The main purpose of using the LIMS System in a lab is to improve the efficiency of sample processing and management. Using LIMS would cut down on the need for manual tasks thereby increasing the accuracy of sample analysis. LIMS captures data automatically, gets processed, and is stored for future reference. The LIMs vendor you choose will define the proceeding process of the software.

Generally, the process of a LIMS is divided into five stages:

  • The sample is logged in after reception.
  • Assignment, scheduling, and tracking of the sample and the analytical workload.
  • Processing and quality control associated with the sample.
  • Storage of data associated with the sample analysis.
  • Inspection, approval, and compilation of the sample data for report generation and further analysis.

Types of LIS Modules Used In Clinical Laboratory:

The features of Laboratory Information System (LIS) have seen evolutionary growth over the years from sample tracking to enterprise resource planning for clinical and specialty laboratories.

A typical workflow pattern of a LIS in a clinical lab flows through three phases:

  • Pre-analytical: Specimen collection.
  • Analytical: testing of the specimens.
  • Post-analytical: Result review.

The LIS modules are used by various laboratory departments like:

  • Blood Bank
  • Immunology
  • Hematology
  • Microbiology
  • Clinical chemistry
  • Histopathology

Various Common Functionalities Used In LIMS:

With the progress in technology, the functions of a LIMS progress too. LIMS software is built in a way to support any upcoming progress while effectively working on a basic set of definite functionalities like the collection of data, tracking of samples, processing, data storage, and report generation.

Some of the core functionalities of LIMS are explained below:

Sample Management:

LIMS was created to help in the process of sample management systems occurring in laboratories. This system gets initiated when a sample is received in a laboratory and gets registered in a LIMS. Since a large number of samples are collected and analyzed in a day, it would be difficult to record the samples without the chance of being confused with other analyses. With LIMS, It would be easier to track the sample if it is labeled and assigned correctly by using RFID on the samples or barcodes.

The information collected and stored via a LIMS would fall under the following criteria:

  • Details about the person whose sample is taken.
  • Details of the doctor/clinic who recommended an analysis.
  • The tests/analysis needed to be taken on the sample.
  • Stages of the sample and destination.
  • Storing procedures.
  • Expected report generation date.
  • Record creation for future purposes.

Workflow Management:

The need for workflow management using a LIMS is as important as Sample management and record-holding. The accuracy of a working system does not just depend on the data; it needs an on-point process assessment where a LIMS system can be used. As the name indicates, workflow management helps automate workflows and assign work if delegated precisely in the software.

All you would have to do for better workflow management using LIMS is:

  • Enter proper codes to direct the LIMS system for a work assignment.
  • Configure the process flow of the work for sample analysis.
  • Assign exact instruments for the particular work.

Workflow management using a LIMS saves time and conducts the job with precision.

EMR/EHR Software:

Electronic Medical Record (EMR) / Electronic Health Record (EHR) is software that collects and stores information on the patient’s medical history in the form of records that can be shared via different healthcare mediums. Many LIMS have this EMR/EHR Software functionality built-in in their system. Using a LIMS with an EHR function will be a huge asset to your lab as the real-time data exchange can be made possible easily.

What is laboratory information...

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Running a productive lab smoothly is tedious. Whether you are dealing with multiple samples or if you have an excessive number of deadlines approaching, following the practical tips given below will help in managing your lab efficiently.


1. Keep an eye on your stuff:

Your inventory covers all the specimens and reagents your lab will need for diagnostic or experimentation analysis. An effective way of sustaining inventory is to use a tool that makes use of barcodes to identify, categorize, and track samples. Regardless, the labels you utilize for vials, racks, tubes, and boxes need to be suitable for the atmosphere in which they will be used. For instance, labels marked ”cryogenic” can come in handy for any reagents stored in freezers or cell lines or specimens stored in liquid nitrogen. 


2. Sustainment is key:

Maintenance of the lab infrastructure is vital to ensure the durability of your reagents and samples. Refrigerators and freezers need to be sustained at the ideal temperature, Co2/O2 levels in each incubator should be controlled carefully, and the stocks of liquid nitrogen and other lab supplies must be replenished. Systems that can control your storage equipment, offering real-time notifications and updates while keeping detailed reports and logs of all parameter-related activity can make this entire process automated, with minimal human intervention, and will ensure that no other thing is missed. These types of systems work with a cloud-based framework and can integrate all reports in a single place and will notify the lab personnel if anything goes wrong.


3. Stay Coordinated:

Spending time in workflow management will enable you to enhance sample traceability, track inventory, improve overall personnel productivity, and more. Incorporating a LIMS (Laboratory Information Management System) is an excellent way to do this as it will note the movement of each sample during the testing process, monitor its custody chain, and enable users to schedule downstream processing, analysis, and testing in a smooth manner. Getting the most out of your LIMS by using barcoded labels is critical as both will aid in sample traceability and tracking. 

Communication and coordination are also vital when incorporating any system that optimizes workflow. Holding regular lab meetings will enable you to create and control any LIMS you wish to utilize and also keep a good record of all lab activities with the help of well-annotated lab books and LIMS. 


4. It’s the system, not the people: 

No matter how organized the labs are, errors will occur. Designing barriers and openly discussing the mistakes will decrease the likelihood of them reappearing. By introducing multiple checkpoints and verifications, you can reduce the chances that the mistakes will stack up causing unanticipated consequences. However, this should not be done without compromising the speed of processing in the lab.  Maintaining lab infrastructure, keeping a managed inventory, and coordinating your workflow are all kinds of barriers that can prevent critical errors. Managing all related data in your lab books will also enable you to resolve the mistakes as each test or experiment can be verified with comprehensive documentation even if the person is no longer a lab member. 


5. Utilize Common Sense: 

Some labs are specialized in carrying out a small set of techniques that need specific labels. For instance, Xylene-resistant labels for histochemistry labs. Regardless, most of the labs do not have tremendous resources with which to buy labels and equipment. Managing a lab cannot be like a one-size-fits-all approach. In this case, it’s crucial to assess what the issues are and to come up with answers from both financial and organizational standpoints. In most cases, simple solutions are enough. For instance, you can have signed-up sheets either online or on paper for machines like biosafety, centrifuges, cabinets, thermocyclers, etc. 


6. Thinking Creatively:

Following the current trends are important. You need to make sure that you’re thinking in a creative manner even for simpler things as it can help avoid issues in the lab and also can enhance the research pace. 


7. Collaboration: 

Efficient communication is crucial regardless of the lab you work in, but with every member consistently working on various techniques or projects, it's possible that they fall out of the habit of collaborating. Lab meetings are a significant way to solve problems, especially at the beginning of the week, so that everyone knows what their tasks are and how to complete them. It’s a good habit to make a relationship with your office mates even outside the lab as this helps to have excellent communication. 


Hope the above blog helped you to know about managing a lab productively and its benefits in depth.


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A Laboratory Information Management System (LIMS): Why Do You Need One?

The adoption of Laboratory Information Management System (LIMS) has become increasingly crucial. This comprehensive guide delves deep into the reasons behind investing in LIMS, shedding light on the myriad benefits it offers to laboratory operations. As we explore the multifaceted facets of LIMS, you'll discover how this powerful tool revolutionizes lab management, enhancing precision, efficiency, and overall quality. Whether you're running a pathology lab, clinical research facility, or any laboratory, this article is your key to understanding why LIMS is a game-changer.


Chapter 1: LIMS Software - A Paradigm Shift in Lab Management

In this digital age, traditional manual processes in laboratories have become a bottleneck, prone to errors and inefficiencies. LIMS software, also known as a laboratory management system, emerges as a game-changer, transforming how laboratories operate. It encompasses a wide range of functionalities, including ERP tools, data analytics capabilities, and virtual software. Let's explore why LIMS is gaining ground in modern laboratories.


1.1. Error-Free Precision

LIMS software is designed to be virtually error-free, a crucial feature for laboratories dealing with sensitive data. Manual handling of laboratory tasks often leads to data mismatches, incorrect readings, and erroneous updates. LIMS ensures impeccable record precision, eliminating these sources of error.


1.2. Centralized Data Access

One of the standout features of LIMS is its ability to provide centralized data access. This means that patient records and reports are easily accessible to authorized personnel. Clinicians, technicians, and other stakeholders can quickly reference and verify patient details. Moreover, LIMS automatically updates critical values and responds to crises, ensuring immediate attention to critical cases.


1.3. Seamless Integration with Instruments

LIMS seamlessly integrates with clinical instruments, streamlining the testing process. It automatically retrieves and stores test results in its primary database, eliminating the need for manual data entry. This not only reduces the risk of errors but also saves valuable time.


Chapter 2: Enhancing Patient Experience through LIMS

2.1. Patient-Focused Updates

LIMS introduces a new level of patient engagement by providing real-time updates. Patients no longer need to anxiously wait for their test results. Instead, they receive automatic updates via SMS or email, along with concise test result summaries. This not only enhances patient satisfaction but also ensures they are well-informed about the progress of their tests.


2.2. Sample Tracking for Quality Assurance

LIMS initiates meticulous sample tracking from the moment a sample is collected. It records clinical reports, phenotypic information, and even freezer locations in great detail. This comprehensive tracking covers freeze and thaw cycles, collection centre details, and responsible clinicians or lab technicians. With LIMS, samples are guaranteed to remain accurate and traceable throughout the entire process, ensuring the highest quality standards.


Chapter 3: Efficiency and Workflow Optimization with LIMS

3.1. Faster Turnaround Time (TAT)

Manual handling of laboratory processes often leads to delays in delivering test results to patients and clinicians. LIMS streamlines these processes, reducing errors and the need for cross-verification. It also efficiently manages and calibrates connected medical instruments, automatically updating them in response to alarming readings. This enhanced efficiency significantly improves the overall Turnaround Time (TAT).


3.2. Hassle-Free Workflow

LIMS takes the hassle out of managing laboratory workflow. The software automates workflow and records maintenance, saving valuable time. As processes are codified within the system, LIMS guides technicians on instrument usage and process handling. This reduces manual interventions for record movement and tracking, making the entire process hassle-free.


3.3. Streamlined Workflow for Doctors and Patients

LIMS offers dedicated login portals for doctors and patients. With preset templates for generating and sending invoices, it streamlines the workflow efficiency. Additionally, doctors and patients can easily access and compare current reports with previous ones, making diagnosis and treatment decisions more efficient.


Chapter 4: Productivity and Quality Control with LIMS

4.1. Enhanced Productivity

LIMS significantly boosts productivity in laboratory settings. It automatically shares lab test results across users, eliminating the need for manual distribution. Quick access to patient history is another productivity booster. Reports are synchronized with physicians' Electronic Medical Records (EMR) for rapid access. Automatic updates and alerts are generated for abnormalities, reducing the need for manual intervention. Furthermore, LIMS enables digital signatures, further cutting down on wait times for approving physical documents.


4.2. Quality Control Assurance

Maintaining quality in laboratory testing is paramount, and LIMS excels in this regard. Through effective Quality Control measures, identifying variations becomes easier. Quality Control results are stored as a database and can be compared to actual results, providing complete control over deviations or errors. With accreditations like NABL and others, LIMS ensures the highest quality standards in results and workflow.



The Future of Laboratory Information Management System(LIMS)

LIMS software is at the forefront of transforming laboratory management. Whether you operate a pathology lab, clinical research facility, or any other type of laboratory, investing in LIMS is a decision that promises to revolutionize your operations. Its integration of advanced technology, error reduction, streamlined workflow, enhanced quality control, and patient-focused features make it an indispensable tool in the healthcare industry. Embrace LIMS to stay ahead of the curve, enhance precision, boost efficiency, and deliver top-notch results while ensuring patient satisfaction.


With LIMS, the future of lab management is brighter than ever. It's time to invest in the future and take your laboratory operations to new heights with this powerful tool. Take advantage of the opportunity to be at the forefront of modern laboratory management. Invest in LIMS today, and reap the benefits of precision, efficiency, and quality.

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MocDoc’s Runnr mobile/web application is designed to handle the sample collection for B2B clients seamlessly. Handling a B2B sample movement can present multiple challenges. One challenge is the potential for delays and miscommunication, leading to samples not reaching the main lab on time. This can disrupt testing timelines and delay crucial results. Another is the manual nature of the process, which increases the risk of human errors such as misplaced or mislabeled samples. Additionally, coordinating logistics and ensuring proper documentation can be time-consuming and prone to inefficiencies.
 
Overall, the lack of a streamlined system for sample movement in the B2B context can result in operational challenges, delays, and errors impacting the efficiency and reliability of laboratory processes.
To overcome this, MocDoc has designed an application that is used by Runnr, the person who is responsible for collecting test samples from the partnered lab and submitting the same at the main lab. This application is used in the pre-analytical phase of the sample lifecycle.

Sample collection for B2B clients - workflow

In the process of handling B2B sample movement between the main and partner labs, several steps are involved. Once a partnered lab requests a test with the main lab, a runnr is assigned by the main lab to facilitate the sample collection and transfer. The partner lab generates a "Test Requisition Form" (TRF) that contains all the necessary details of the requested tests. This form, along with the test sample, is then shared with the assigned runnr.

The TRF serves as a crucial document as it outlines the specific tests to be conducted on the collected samples. The identification of the samples is typically done through barcodes that link them to the associated patients, ensuring accurate tracking and traceability.

The assigned runnr is responsible for ensuring the safe and timely delivery of both the TRF and the test sample to the main lab. Upon receiving the samples, the main lab validates and accepts them, carefully verifying the information provided in the TRF. Subsequently, the main lab proceeds to process the samples for the requested tests, following the established protocols and procedures.

Efficient coordination and communication between the partner and main labs, as well as the diligent execution of the sample transfer process by the runnr, are essential to ensuring the smooth flow of samples and accurate testing outcomes.

Benefits of using the Runnr app to handle B2B sample movement

Using the Runnr app, the personnel designated to handle the sample movement between the partnered and the main lab can perform the process effectively, as it is easy to generate and share the TRF, and also to record progress from time to time. Here are a few benefits of using the Runnr app
 
●     The application enables users to generate and submit the TRF online, eliminating the need for manual paperwork and reducing the likelihood of errors such as missing records.
●     Barcodes are generated to uniquely identify test samples in relation to patients, streamlining the handling process and ensuring accurate testing. They facilitate the correlation of samples with the correct patients and requested tests, reducing errors.
●     Sample movement is closely monitored as the runnr transfers them between labs, enabling efficient tracking of delays and issues.
●     Prior to testing, a meticulous verification process confirms the correct sample. This adds an extra layer of quality control, minimizing errors and mix-ups.
The combined use of barcodes, monitoring, and verification enhances the overall accuracy and efficiency of the testing procedure.

Incorporating a dedicated mobile/web application for B2B sample movement has revolutionized the process, eliminating manual efforts and errors. Seamless generation and submission of TRFs, along with barcode identification, ensure accurate testing and correlation with patients. With real-time monitoring, delays can be promptly addressed.
Embrace the power of technology for efficient and error-free sample handling. Try the Runnr app today and streamline your B2B sample management. Unleash the complete potential of your laboratory with our Mocdoc LIMS Software.


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